This article is sourced and translated from Ganoderma Magazine (Issue 88). It is a report of a scientific study concluding that the combined therapy of Lingzhi triterpenoids and Gefitinib (sold under the brand name Iressa) improves lung cancer and reduces toxicity.

Lung cancer ranks among the most common primary cancer worldwide and is a leading cause of deaths amongst men and second amongst women. 

There are 2 types of lung cancer:

(i) Small cell lung cancer 

(ii) Non-small cell lung cancer (NSCLC).

Advances in medical discoveries and technologies have improved the therapeutic methods for lung cancer. Gefitinib (trade name: Iressa) is a targeted drug commonly used to treat late-stage metastasis NSCLC and other cancer, like breast cancer. However, after 10 to 16 months of therapy, patients normally develop resistance to the drug thereby frustrating the treatment process.

Therefore, seizing the effective curative period of Gefitinib is crucial to the control of the metastatic cancer cells. At the same time, reducing the side effects of the drugs would enable the patients to be in a better state to fight the illness and reverse the situation. A joint study by the Dept of Oncology, Yantai Hospital of TCM and School of Medicine, Tibet University, found that the combination of Lingzhi triterpenoid and Gefitinib therapy increases efficacy and reduces toxicity. The study, which was headed by Wei Liu, is titled Ganoderma Triterpenoids attenuate tumour angiogenesis in lung cancer tumour-bearing nude mice, and was published in Pharmaceutical Biology in 2020.

The Experiment

Human lung cancer cells (A549) were cultured and then injected into immune-deficient mice (BALB/c). When the tumor grew to around 6-8 mm in diameter, the mice were randomly divided into 4 groups and administered for 14 days in the following manner:

(i) Saline group (control) - intragastric injection with saline daily.

(ii) GLT group - intragastric injection with Lingzhi triterpenoids (1g/kg daily).

(iii) GEF group - intraperitoneal injection with gefitinib (15mg/kg daily).

(iv) GLT + GEF group - combination of (ii) and (iii).

The mice were sacrificed and analysed on the 15th day.

The Results

It was found that the tumor volume of GLT, GEF and GLT+GEF groups were significantly lower than the Saline (Control) group. The inhibition rates of the tumors were GLT 37%, GEF 43% and GLT+GEF 52%. This suggested that although GLT and GEF may inhibit the rate of tumor growth individually, the combined effect is higher. The inhibition was due to the accelerated apoptosis of cancer cells and at the same time inhibiting tumor angiogenesis.

What is Angiogenesis?

Angiogenesis is the process through which new blood vessels grow from existing blood vessels. In order to survive, tumors need to continuously grow new blood vessels to link to existing blood vessels for oxygen and nutrients. This also explains how cancer cells tend to spread (metastasize) to the surrounding tissues and other parts of the body. Therefore, the density of micro-vessels (microvascular) in the tumor tissues will be key to the continuous growth of tumors.

The study made a histological (immunohistochemical) analysis of the tumor tissues of the various group. Quantifying the analysis showed that GLT and GEF groups had lower microvascular density (MVD) than the control group, indicating inhibition of tumor angiogenesis. However, the efficacy was much better when GLT was combined with GEF.

The Side Effects

The mice were weighed on the 1st, 8th and 15th day of the study. The results showed, after the 8th day, the weight of:

- The GEF group dropped significantly.

- The GLT group was stable.

- The GLT+GEF group maintained closer to that of normal healthy mice.

This indicated that the combined therapy of GLT+GEF reduces the side effects of GEF as weight is normally an indicator of well being.

In their observation of the mice, the study found that:

- The GEF group showed signs of agitation and drowsiness, reduced physical activity, decreased feeding and dull skin colour. This could be due to the effects of administrating GEF.

- The GLT+GEF group showed no obvious agitation and drowsiness, accessed water and food without difficulty, and exhibited improved skin color compared to the GEF group.

The results indicated that GLT played a role in alleviating the effects caused by GEF.

Conclusion

The study showed that Lingzhi triterpenoids do not affect the efficacy of Gefitinib but enhanced it.

Note: The study did not dwell into the details of the Lingzhi triterpenoids being used and what was the effective content. The dosage of 1g/kg used in the study was high, but one should note that the study is for a short duration and the researchers would like to know the results within a short span of time. A reasonable dosage is necessary for Lingzhi to take effect in this kind of situation

(Source: Shuang Hor Video Depository, 19/12/2021)

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In November, 2023, Ms Chun-Ching Wu (Ginny Wu) presented 12 testimonies which illustrate how to effectively use Equivalent Target Lingzhi to help manage various health conditions. 

Lingzhi Gannoderma has been widely researched over the years and its ability to fight virus is well-known. So when the covid-19 pandemic happens, researchers simply do additional research to prove that it also helps to fight this particular virus.

Six Research Findings

Report 1 - China (Issue 89 (2021) of Healthy Ganoderma Magazine)

I have translated an extract of the above research news:

Ganoderma lucidum polysaccharides effectively inhibit the growth of new coronaviruses in animal lungs. Since the outbreak of covid-19, Ganoderma lucidum's excellent ability to regulate immunity has been regarded as the theoretical basis for Ganoderma to help fight the epidemic. The report published in the February 2021 issue of PNAS (Proceedings of the National Academy of Sciences) by a team led by the Genomic Research Center of the Academia Sinica has finally provided direct evidence for Ganoderma lucidum to suppress the SARS-Cov-2.

The researchers first infected lab hamsters with covid-19, and then orally administered Ganoderma extract the next day, at a daily dose of 200 mgkg. After 3 days of treatment, it was found that the amount of covid-19 in the lungs of these hamsters was only about half of that of the untreated control group. Since the weight of the hamsters did not drop significantly, the researchers concluded that the multi-extract of Ganoderma lucidum can be used without any concerns about food safety.

Ganoderma lucidum effectively inhibits the proliferation of covid-19 in the body. Although this is only a result of an experiment on hamsters, but because the respiratory tract tissues of hamsters is similar to that of humans, when the immune system is stimulated by infection, it also produces cytokines similar to humans, so the experimental results have their reference value.

This study is not an independent study of Ganoderma lucidum. The researchers intend to select ingredients that "can inhibit new coronavirus infections". Therefore, they used 2 rounds of in-vitro cell experiments to comprehensively evaluate the safety and effectiveness of more than 3,000 existing water extracts and Chinese herbal medicines. 

In the end, 7 "potential devices" including Ganoderma lucidum extracts were selected. The result is a reminder that neither animals nor humans is a single cell being, but are composed of multiple cells - a whole set of systems are fighting the virus. The dazzling performance of Ganoderma lucidum in the body must be related to the enhancement of the antiviral ability of the whole system (including the immune system). 

A brief explanation of the graph above..

Mefloquine, Nelfinavir, Salinomycin and Thioguanine are drugs to treat malaria, HIV, bacteria (antibiotics) and leukemia respectively. Although Mefloquine and Nelfinavir are more effective than Lingzhi in inhibiting covid-19, the drugs can only be used for treatment, and can never be taken to prevent infection.

RF3 is an extraction of polysaccharide from Lingzhi. The experiment proves that Lingzhi polysaccharide can effectively inhibit the survival of covid-19 in lungs.

Perilla Frutescens and Mentha Haplocalyx are plants in the mint family. They are also known to be effective in fighting coronavirus. You may think in that case, they are a good solution as they are cheap. 

However, the time taken to prepare and the volume you have to drink is not feasible. According to the experiment, you need to spend 4 hours to extract 1g of herbs in 20 ml (20,000 mg or 20 g) of water. In the animal experiment, equivalently, they need to take 200 mg (0.2 g) of water extract per 1 kg of body weight per day to convert to the amount required for human consumption. Therefore, it is not feasible in terms of the volume of raw material and time needed to prepare, not to mention the quality and consistency of active ingredients in the plants. 

In conclusion, not only is Lingzhi safe to consume, it is also convenient as it is readily available. 

Taking a step back, let's try to understand how covid-19 attacks lung cells..

Dear Readers,
I hope you like what you read so far.
Do you want to find out what are the other 5 research reports?

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Lingzhi (also known as Ganoderma) is not something new. More than 3,000 years ago, Shen-nong Pharmacopiea has already recorded the existence of Lingzhi. In the olden days, only the Emperor was able to consume this precious herb. Lingzhi was considered as the best medicine because it is non-toxic and long-term consumption maintains youthfulness. 

Today, with modern research, it confirms that Ganoderma Lucidum is a functional food. It is food, as opposed to medicine. It is very safe to be consumed. It is very widely researched and its efficacy is proven. The triterpenoids, ganoderic acids, lucidenic acids and polysaccharides which have been extracted and isolated from Ganoderma species are the components that perform the functions. People in the ancient times did not know this. But today, the researchers are able to identify more and more of these effective components.

Drugs are newly developed and we don't know their long term side effects. Only time can tell. However, with Lingzhi, we already know what it can do. People who take Lingzhi can live longer; they have less illnesses etc. We just don't know the mechanisms of how it works. The research directions are to find out how Lingzhi does it eg. triterpenoids performs this function, ganoderic acid performs that function etc. In other words, we already know Lingzhi's benefits (as below), unlike drugs.

Body Diagram

Lingzhi from Shuang Hor is considered to be the market leader. Not only is Shuang Hor able to extract the triterpenoid component, it can also purify it into ganoderic acids.

What are the major components of Lingzhi and their functions?

Triterpenoid

- Modulate immunity by calming down overly active immune cells.

- Reduce cholesterol. Such chronic diseases can weaken your immune system.

- Promote disaggregation of thrombi. One of the causes of death of covid-19 is blood clots. Triterpenoid can help dissolve the clots and allow the blood to circulate smoothly.

- Improve elasticity of blood vessels.

- Increase mobility of blood flow.

- Enhance liver function (detoxification).

- Alleviate allergic conditions.

Macromolecular polysaccharides

- Fortify immune defence.

- Remove free radicals.

- Promote regeneration of liver cells.

- Strengthen the physique.

How does your immune system work?

The first line of defence are the Phagocytes. When there's an invasion of foreign substances into our body, the Phagocytes (including Macrophage) are the first to react. If they are overwhelmed, the T-cells will be activated. They will destroy the invaders and at the same time, send messages to B-cells to produce antibodies (weapons) to be used to fight against the invaders. Another group are the Natural Killer Cells which fight against cancerous cells. This is essentially how our immune system works. 

Lingzhi is able to balance or modulate our immune system - what is too weak will be enhanced, and what is too hyper will be calmed down. Lingzhi works on all systems in the body, including the Immune system and Respiratory system, which are directly affected by the covid-19.

Shuang Hor Lingzhi Ganoderma

Shuang Hor Lingzhi has been endorsed with 2 important certifications from the Health Ministry of Taiwan.  The certification #A00003 affirms that Yung Kien Ganoderma helps with 5 functions and 2 functions in relation to our immune system and liver respectively. There is no other product that can claim that they have all these functions.

The certification above proves that Shuang Hor's Lingzhi is a quality Lingzhi. In addition to the certification from the Health Ministry of Taiwan, it also has:

• ISO 9001 certification
• GMP and GLP certifications
• TQF certification 
• Accepted by JHFA (Japan Health Food Authority) 
• Accepted by HSA (Singapore Health Sciences Authority) 
• International Halal certifications.

5 Trump Cards of Shuang Hor Lingzhi Against Covid-19

1) Safe. It is so safe that newborn babies can consume; so covid-19 patients can definitely consume.

2) Prevention. Meaning, if you don't have covid-19, you can take Lingzhi to prevent it, unlike drugs where you can only take it after contracting the disease.

3) Dual regulating. If your immune system is too low, it helps to improve. If your immune system is too high, it helps to bring down. 

4) Effective. It is effective at every stage of your life, whether you're healthy, at pre-illness stage, sick or severely sick. This depends on how much you take and how long you take it. Many researches have proven that Lingzhi is also effective against covid-19.

5) Multi-function. Most drugs are single function eg. HBP drugs are only able to treat HBP problem. Covid-19 vaccines are only for covid-19. Whereas for Lingzhi, it helps with your overall health (as seen from the above Body Diagram).

Equivalent Target Lingzhi - Yung Kien I (YK Immune)

Why do I recommend you to take YK Immune for Covid-19? 

Because YK Immune is targeted, meaning it is very focused on your immune system. It builds your immune system to the level you want and at the same time, regulates it. Hence, it is a more convenient and speedier solution, especially in the current situation.  Some points on YK Immune in a nutshell:

Dear Readers,
I hope you like what you read so far.
Do you want to find out why I recommend you to take YK Immune for covid-19? And how to take it to achieve the Best Results?

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We can say that the lungs has the first contact with the external environment. It is the first doorway for pathogens to enter our body because as we breath in, the air goes straight to the lungs.

Common diseases related to respiratory system:

(a) Asthma, where the airways narrow and swell, making breathing difficult, and trigger coughing, wheezing and shortness of breath. Common asthma attack triggers include inhaling smoke, cold air, GERD and stress. It's a type of auto-immune disorder where the Th2 becomes hyperactive.

(b) Pneumonia, which is lung inflammation caused by bacterial or viral infection. The air sacs in the lungs (alveoli) are filled with fluid or pus. X-rays show affected area as white spots (called pulmonary infiltrates).

Pulmonary edema occurs when alveoli fill up with excess fluid (often caused by congestive heart failure).

(c) Bronchitis, which is inflammation of the lining of the bronchial tubes, caused by viral or bacterial infection, or breathing in things that irritate the lungs.

When you experience breathing difficulty, deep breathing exercise help. Especially when you travel to cold countries, you may experience constrictions to your lungs if you are not used to the temperature change. The inhalation of such cold air may cause your WBC activity (immune system) to suddenly drop (as they function optimally at 37'C). Hence if there's germs in the air, you can easily get infected.

A suggestion for pneumonia cases:

(i) Take at least 15 YK1 or 4 YK2, open up the capsules, pour the powder into warm water and sip slowly. Let the Lingzhi powder stick on the oesophagus.
After 2-3 minutes, drink down the residual from the cup.

(ii) Calmly sit down and take deep breaths for 10 mins.

(iii) If still not able to breath well, put 3 Lactoberry into the throat without drinking any water.
After 3-5 mins, drink room temp water.

(iv) Heat therapy - use the hairdryer to blow at the meridian points between nipples and just below the neck for 5-10 mins. It raises your body temp back to 37'C, and your immune system is able to perform again.

Testimony:
Ms J had severe pounding headache when she visited Kunming because the weather was too cold. She put 2-3 YK1 (after removing capsules) under her tongue. Within 5 mins, she vomited and felt relief from her headache.

A suggestion for bronchitis cases:
It's better to take YK2 because many a times, it could be due to autoimmune system disorder. The high content of triterpenoid of YK2 is better (at least 4 YK2), unless you swallow at least 20 YK1, where the triterpenoid level would then be sufficient.

TCM Perspective

The colon and lung meridian points are inter-related. If you experience constipation continuously for 3-5 days and the quality of your stools is poor, this indicates there is a drop in the health of your respiratory system. This is because the meridian points of large intestines and lungs are linked.

Other Symptoms of unhealthy respiratory system:
- phlegm, throat irritation, itchy throat, runny nose
- negative emotion (sadness)
- difficulty perspiring
- rough skin condition
- blisters all over body.

Colon meridian point: outer side of index finger.
Lung meridian point: outer side of thumb.
Meeting point is between between these 2 fingers on the back of the hand and further up on the wrist.
People with weak lungs will feel sharp pain when these points are massaged. There may even be appearance of water blisters.

Solutions

For people with lung problem, allergy and asthma, taking Lactoberry helps as it improves the quality of the bacteria in the intestines, and eventually improves quality of lungs. When the digestive system health improves, your bowel movement is smoother and the quality of your breathing also improves.

Take care of your diet - reduce the consumption of spicy food and take more white colour food to nourish the lungs (white fungus, white lily bulb, barley, almond powder drink). Take pollen in capsule form, rather than granular form.

Take care of your emotions.

Why do some  people wake up with runny nose and sneezing in the morning?

- Aircond is too cold.
- Aircond filter is dirty.
- Bedroom has a lot of allergens and dust.
- Bedsheet has a lot of dust mites.

Quick fix: Slice a big red onion in half and leave it on a plate in the room. However, it's only temporary fix and doesn't address the root cause of the problem. This is because onions can kill bacteria.

Testimony:
Two children suffer from severe asthma. After taking Lingzhi and Pollen, the healing reaction is their cough becomes worse. One coughed out an excess amount of phlegm; the other was sent to hospital to draw out the phlegm. After that, they don't have the attacks anymore. In other words, do not panic, Lingzhi and Pollen are safe, but the consumers need to have faith and patience to go through the episode.

Lung Cancer

Lung cancer is one of the top 10 causes of death. It doesn't happen overnight. It is discovered that 20-30 years prior to being diagnosed with lung cancer, these people had dry cough. They would see the doctor, take cough syrup, the symptoms disappear. When the cough recurs 2-3 months later, they repeated the cycle of seeing doctor. This could continue for 20-30 years. Suddenly they have a severe bout of cough and when they go for checkup, the doctor would pronounce them as stage 4 lung cancer patient.

When particles stick to the wall of the alveoli, the exchange of air can't function properly, and that's why people experience dry cough. Another way of looking at it is that when one experiences dry cough, it's a sign that the immune system is working, and is trying to cough out the toxins from body. But if the lungs is weak, nothing would come out. Cough syrup contains steroids and suppress the activities of immune cells, making it appear that the irritations have gone. However, toxins are actually reabsorbed back into the body. Accumulation of toxins over a period of time increases the severity.

Please email me at askfuiping@gmail.com to place your order. I am an Authorised Distributor.

The health of our lungs is affected by:

(a) Environmental pollution e.g. while cleaning the house
(b) Virus / bacterial infections
(c) Smoke
(d) Radiation therapy.

Our lungs will be inflamed and damaged from prolonged exposure to these elements. When this happens, the lungs will start to lose its function. Premature babies tend to have weaker lungs, because lungs is the last organ to be developed in the womb.

A news release by World Health Organisation on 2 May 2018 states that 90% of the world population breathe polluted air. We can pick and choose the food we eat and the water we drink, and choose a healthier alternative. But we cannot choose to breath only healthier air instead of dirty air.

New data reveals that we breathe air containing high levels of pollutants like black carbon which penetrate deep into the lungs and cardiovascular system. WHO estimates that around 7 million people die every year from exposure to fine particles in polluted air that lead to diseases such as stroke, heart disease, lung cancer, chronic obstructive pulmonary diseases (COPD) and respiratory infections, including pneumonia.
Dear Readers,
Do you want to find out more?
You can only get the full text of this post in my Private blog.
If you want a copy, please email me at askfuiping@gmail.com.
This info is reserved exclusively for my Consumers and Business Partners only.

If you are already authorised, please click on this link..
https://pingofhealthexclusive.blogspot.com/2018/12/inflammation-of-lungs.html


If you are new to my blog and want to find out more, please email me at askfuiping@gmail.com for a FREE consultation on the health of your lungs and how you can improve it.