Our immune cells can attack our own body cells under conditions of stress or due to genetics. The attacks can happen on any organ in our body (as the immune cells are all over the body), thus causing chronic inflammation under the category of auto-immune system disorders. Some common ones are rheumatoid arthritis, SLE, hyperthyroidism, nephritis, allergy etc.
Scientific Experiments
It has been proven that Lingzhi can prevent auto-immune diseases. A few experiments were conducted to verify how Ganoderma works. These research articles are extracted from the presentation by Ms Yu-Chi Cheng during her talk (pgs 31-35):
Study 1
In a study by Lai (Ning Shen), et al., published in the Lupus Journal in 2001, it was proven that Ganoderma tsugae (Yung Kien Ganoderma) can prevent autoantibody formation and prolong the survival rates of lab mice with lupus condition. In the experiment, mice with lupus were divided into 2 groups and fed with prednisolone steroids or Gannoderma extract.
It was found that Lingzhi:
- improved the survival rate of lupus mice
- decreased the amount of proteinuria
- decreased serum levels of anti-dsDNA autoantibody
- showed evidence of decreased perivascular and parenchyma mono-nuclear cell infiltration in vital organs.
Study 2
A study by Pi, et al., was published in the SpringerPlus Journal in 2014.
Allergic asthma is an inflammatory disease of the airways mediated by Th2 immune responses and characterised by airway hyper responsiveness (AHR). The study found that the polysaccharide component of Ganoderma formosanum stimulates the activation of dendritic cells and primes Th1 cells.
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